南五味子属植物三萜类化合物及其药理作用研究进展

A Review of Triterpenoids and Their Pharmacological Activities from Genus Kadsura

摘要: 五味子科南五味子属植物在民间治疗类风湿性关节炎和胃肠疾病具有悠久历史，研究表明其主要活性成分为木脂素和三萜类化合物。三萜类化合物是五味子科五味子属和南五味子属植物的主要差异性化学成分。本文对近三十年（1987-2017年）南五味子属植物中的214种三萜类化合物的结构分类及其药理活性的研究进展进行了系统综述，以期为进一步的研究提供理论参考。

Abstract: Plants in genus Kadsura, belong to the Schisandraceae family including genus Schisandra and genus Kadsura, revealed folk efficacy and medicinal application in the treatment of rheumatoid arthritis and gastroenteric disorders for a long history. Previous study indicated that plants from genus Kadsura mainly contain lignans, triterpenoids and essential oils, and showed the active compounds were lignans and triterpenoids. Among all compounds from Schisandraceae family, the triterpenoids between the genus Schisandra and genus Kadsura had obvious differences. In this paper, we reviewed 214 triterpenoids and their pharmacological activities reported from genus Kadsura in the past 30 years (from 1987 to 2017), aiming to provide reference for further study.